GENOMIC AND BIOINFORMATIC SERVICES
Helixio offers a wide range of Genomic and Bioinformatic Services in the fields of human, animal or plant biology and diseases, to meet the needs of life scientists from academia, public research institutes or R&D laboratories of pharmaceutical, cosmetic, agrofood or environmental industries using the most common technologies:
Next Generation Sequencing (Whole Genome Seq, Whole Exome Seq, DNA Targeted Seq, RNA Seq, Methyl Seq…), MicroArrays (Gene Expression, CGH, CNV, Genotyping...), RT-QPCR, PCR…
Our multidisciplinary team ensures a comprehensive scientific and technical support to your projects which can concern both eukaryotic and prokaryotic genomes, even the most unusual ones..
NextGeneration Sequencing
- De novo sequencing
- Analysis of disease region that segregate in families
- Identification of functional variations that could be responsible for mendelian or common diseases
- Identification of DNA variations in enriched genes or regions of interest
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DNA Seq
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Target Enrichment
Customized genomics
- Creation of a custom target enrichment library to sequence specific genes or regions of interest
- Design of custom microarrays for specific regions or for species non available on commercial catalogs
- SNP selection for genotyping assays
Gene expression profiling
- Identification of genes whose expression changed in response to an experimental parameter (drug, phenotype, disease...)
- Validation of predicted genes
- Identification of alternative splice variants
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Microarray Expression
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Quantitative PCR
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RNA Seq
Comparative genomic hybridization
- Identification of genomic copy number variants
- Detection of chromosomal aberrations for cancer classification
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Microarray CGH
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Microarray CNV
SNP genotyping
- Identification of SNP among alleles within or between populations
- Measurement of predisposition to disease
- Genetic linkage analysis
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Microarray SNP Genotyping
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Microarray CGH+SNP
Expression Regulation
- Identification of miRNA whose expression changed in response to an experimental parameter
- Identification of the effects of an experimental parameter according to DNA methylation status
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Microarray miRNA
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Microarray Methylation
Data Custom Analysis
- Data quality control
- High throughput data analysis
- Data interpretation
- Data integration
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Open-source bioinformatics tools
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Commercial applications
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Custom pipelines and workflows
